{"id":252368,"date":"2024-07-22T21:32:04","date_gmt":"2024-07-22T19:32:04","guid":{"rendered":"https:\/\/dgkl.de\/nmr-spectroscopy\/"},"modified":"2025-05-16T11:34:45","modified_gmt":"2025-05-16T09:34:45","slug":"nmr-spectroscopy","status":"publish","type":"page","link":"https:\/\/dgkl.de\/en\/the-dgkl\/areas-of-expertise\/nmr-spectroscopy\/","title":{"rendered":"NMR Spectroscopy"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; custom_padding_last_edited=&#8221;on|tablet&#8221; disabled_on=&#8221;on|on|off&#8221; admin_label=&#8221;Sektion&#8221; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; use_background_color_gradient=&#8221;on&#8221; background_color_gradient_direction=&#8221;59deg&#8221; background_color_gradient_stops=&#8221;#0b2649 13%|rgba(255,255,255,0) 100%&#8221; background_color_gradient_overlays_image=&#8221;on&#8221; background_image=&#8221;https:\/\/dgkl.de\/wp-content\/uploads\/2024\/07\/Die-DGKL-3-1.png&#8221; background_enable_video_mp4=&#8221;off&#8221; 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admin_label=&#8221;Sektion&#8221; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; use_background_color_gradient=&#8221;on&#8221; background_color_gradient_direction=&#8221;59deg&#8221; background_color_gradient_stops=&#8221;#0b2649 13%|rgba(255,255,255,0) 100%&#8221; background_color_gradient_overlays_image=&#8221;on&#8221; background_image=&#8221;https:\/\/dgkl.de\/wp-content\/uploads\/2024\/07\/Die-DGKL-3-1.png&#8221; background_enable_video_mp4=&#8221;off&#8221; width=&#8221;100%&#8221; custom_margin=&#8221;0px||0px||false|false&#8221; custom_padding=&#8221;50px||50px||true|false&#8221; custom_padding_tablet=&#8221;0px||0px||false|false&#8221; custom_padding_phone=&#8221;10px||10px||true|false&#8221; top_divider_color=&#8221;#ffffff&#8221; top_divider_height=&#8221;35px&#8221; top_divider_repeat=&#8221;1x&#8221; top_divider_flip=&#8221;vertical|horizontal&#8221; animation_style=&#8221;fade&#8221; animation_speed_curve=&#8221;ease&#8221; hover_enabled=&#8221;0&#8243; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221; custom_css_before_last_edited=&#8221;on|tablet&#8221; custom_css_before_phone=&#8221;display:none;&#8221; title_text=&#8221;Die DGKL 3&#8243; sticky_enabled=&#8221;0&#8243;][et_pb_row column_structure=&#8221;2_3,1_3&#8243; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; width=&#8221;100%&#8221; custom_margin=&#8221;0px|auto|0px|auto|false|false&#8221; custom_margin_tablet=&#8221;0px||0px||false|false&#8221; custom_margin_phone=&#8221;0px||0px||false|false&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; custom_padding=&#8221;30px|30px|30px|30px|true|true&#8221; border_radii=&#8221;on|10px|10px|10px|10px&#8221; global_colors_info=&#8221;{}&#8221; background_enable_color=&#8221;off&#8221; title_text=&#8221;Die DGKL 3&#8243; background_enable_image=&#8221;off&#8221; hover_enabled=&#8221;0&#8243; sticky_enabled=&#8221;0&#8243;][et_pb_column type=&#8221;2_3&#8243; _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text disabled_on=&#8221;on|off|on&#8221; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; header_font=&#8221;|700|||||||&#8221; header_text_color=&#8221;#FFFFFF&#8221; header_font_size=&#8221;65px&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h1>NMR Spectroscopy<\/h1>\n<p>[\/et_pb_text][et_pb_text disabled_on=&#8221;off|on|on&#8221; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; header_font=&#8221;|700|||||||&#8221; header_text_color=&#8221;#FFFFFF&#8221; header_font_size=&#8221;45px&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h1>NMR Spectroscopy<\/h1>\n<p>[\/et_pb_text][et_pb_divider color=&#8221;RGBA(255,255,255,0)&#8221; divider_weight=&#8221;21px&#8221; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; use_background_color_gradient=&#8221;on&#8221; background_color_gradient_direction=&#8221;90deg&#8221; background_color_gradient_stops=&#8221;#b51f29 0%|rgba(181,0,12,0.45) 100%&#8221; max_width=&#8221;100px&#8221; module_alignment=&#8221;left&#8221; min_height=&#8221;10px&#8221; max_height=&#8221;3px&#8221; custom_margin=&#8221;0px||0px||false|false&#8221; custom_padding=&#8221;0px||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_divider][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.25.1&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.27.0&#8243; background_color=&#8221;#FFFFFF&#8221; width=&#8221;100%&#8221; custom_padding=&#8221;100px||100px||true|false&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row column_structure=&#8221;2_3,1_3&#8243; use_custom_gutter=&#8221;on&#8221; gutter_width=&#8221;2&#8243; make_equal=&#8221;on&#8221; custom_padding_last_edited=&#8221;on|phone&#8221; _builder_version=&#8221;4.27.0&#8243; width=&#8221;100%&#8221; width_tablet=&#8221;80%&#8221; width_phone=&#8221;90%&#8221; width_last_edited=&#8221;on|phone&#8221; max_width_tablet=&#8221;&#8221; max_width_phone=&#8221;90%&#8221; max_width_last_edited=&#8221;on|tablet&#8221; custom_padding=&#8221;0px||34px||false|false&#8221; custom_padding_tablet=&#8221;||0px||false|false&#8221; custom_padding_phone=&#8221;||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;2_3&#8243; _builder_version=&#8221;4.27.0&#8243; custom_padding=&#8221;16px|50px||0px|false|false&#8221; custom_padding_tablet=&#8221;0px|||0px|false|false&#8221; custom_padding_phone=&#8221;0px|||0px|false|false&#8221; custom_padding_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; header_3_font=&#8221;Anek Bangla|700|||||||&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h3 class=\"\">Identifying Structures<\/h3>\n<p>[\/et_pb_text][et_pb_divider color=&#8221;RGBA(255,255,255,0)&#8221; divider_weight=&#8221;3px&#8221; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; use_background_color_gradient=&#8221;on&#8221; background_color_gradient_direction=&#8221;90deg&#8221; background_color_gradient_stops=&#8221;#203367 0%|#e41c3c 100%&#8221; max_width=&#8221;100px&#8221; module_alignment=&#8221;left&#8221; max_height=&#8221;3px&#8221; custom_margin=&#8221;0px||37px||false|false&#8221; custom_padding=&#8221;0px||0px||false|false&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_divider][et_pb_text _builder_version=&#8221;4.27.0&#8243; link_text_color=&#8221;#1f3267&#8243; custom_margin=&#8221;10px||10px||true|false&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>In NMR spectroscopy, in addition to the classical metabolites from clinical chemistry such as glucose and cholesterol, numerous other measurands like amino acids, medications, and many other substances are detected. The number of identified substances in the libraries is constantly growing. Compared to other measurement methods, the quantification of defined metabolites is relatively simple, as a universal standard is sufficient and specific standards are not required for all metabolites.  <\/p>\n<p>Furthermore, NMR spectroscopy is a useful method in the field of metabolomics, as it not only captures individual substances but can also detect metabolic signatures composed of many substances and spectra. These metabolic signatures contribute to better metabolic characterization of individuals and patients. This allows early detection of health risks in certain groups of people, enabling us to describe and thus diagnose subclinical diseases that have previously remained undetected.  <\/p>\n<p>The &#8220;NMR Spectroscopy&#8221; section aims to address the following topics to facilitate good translation of this technology into laboratory medicine:<\/p>\n<ul>\n<li>Strengthening collaboration between centers using this technology<\/li>\n<li>Standardization of measurement protocols to achieve the best possible comparability between platforms<\/li>\n<li>Dialogue on evaluation methods for NMR spectra<\/li>\n<li>Establishment of spectral databases<\/li>\n<li>Development of proficiency tests to document the quality of examinations<\/li>\n<li>Development of signatures that enable the detection of subclinical diseases (Deep phenotyping; a characterization of individuals based on metabolic changes measured by NMR spectroscopy)<\/li>\n<li>Close collaboration with other sections within the DGKL to leverage synergies<\/li>\n<\/ul>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; admin_label=&#8221;Column&#8221; _builder_version=&#8221;4.27.0&#8243; background_color=&#8221;#f8f8f8&#8243; custom_padding=&#8221;20px|40px|20px|40px|true|true&#8221; animation_style=&#8221;zoom&#8221; animation_intensity_zoom=&#8221;3%&#8221; custom_css_main_element=&#8221;-webkit-backdrop-filter: blur(5px);||backdrop-filter: blur(5px);&#8221; border_width_left=&#8221;5px&#8221; border_color_left=&#8221;#AB1638&#8243; box_shadow_style=&#8221;preset1&#8243; box_shadow_color=&#8221;rgba(0,0,0,0.15)&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; header_3_font=&#8221;Anek Bangla|700|||||||&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h3 class=\"\">Contact<\/h3>\n<p>[\/et_pb_text][et_pb_divider color=&#8221;RGBA(255,255,255,0)&#8221; divider_weight=&#8221;3px&#8221; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; use_background_color_gradient=&#8221;on&#8221; background_color_gradient_direction=&#8221;90deg&#8221; background_color_gradient_stops=&#8221;#203367 0%|#e41c3c 100%&#8221; max_width=&#8221;100px&#8221; module_alignment=&#8221;left&#8221; max_height=&#8221;3px&#8221; custom_margin=&#8221;0px||37px||false|false&#8221; custom_padding=&#8221;0px||0px||false|false&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_divider][et_pb_text _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<div class=\"dgkl-contact-person-position\">\n<div class=\"dgkl-contact-person-sidebar-item\">\n<div class=\"dgkl-contact-person-position\">\n<div class=\"dgkl-contact-person-sidebar-item\">\n<div class=\"dgkl-contact-person-position\"><strong>Chairperson:<\/strong><\/div>\n<div class=\"dgkl-contact-person-name\"><span>Prof. Dr. med. Dipl. Biol. Astrid Petersmann  <\/span><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;30px||||false|false&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<div class=\"dgkl-contact-person-position\">\n<div class=\"dgkl-contact-person-sidebar-item\">\n<div class=\"dgkl-contact-person-position\">\n<div class=\"dgkl-contact-person-sidebar-item\">\n<div class=\"dgkl-contact-person-position\">\n<div class=\"dgkl-contact-person-sidebar-item\">\n<div class=\"dgkl-contact-person-name\"><strong>Deputy Chairperson: <\/strong><\/div>\n<\/div>\n<div class=\"dgkl-contact-person-sidebar-item\">\n<div class=\"dgkl-contact-person-name\"><span>Univ.-Prof. Dr. med. Matthias Nauck<\/span><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<p>[\/et_pb_text][et_pb_button button_url=&#8221;mailto:sek_nmr-spektroskopie@dgkl.de&#8221; button_text=&#8221;Email&#8221; button_alignment=&#8221;center&#8221; _builder_version=&#8221;4.27.0&#8243; _module_preset=&#8221;default&#8221; custom_button=&#8221;on&#8221; button_text_color=&#8221;#FFFFFF&#8221; button_bg_color=&#8221;RGBA(255,255,255,0)&#8221; button_bg_use_color_gradient=&#8221;on&#8221; button_bg_color_gradient_direction=&#8221;45deg&#8221; button_bg_color_gradient_stops=&#8221;#ab1638 34%|#d81c45 74%&#8221; button_bg_color_gradient_unit=&#8221;pc&#8221; button_border_width=&#8221;0px&#8221; button_border_color=&#8221;#ab1638&#8243; button_use_icon=&#8221;off&#8221; custom_margin=&#8221;30px||||false|false&#8221; custom_css_main_element=&#8221;width:100%;&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_button][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p><div class=\"et_pb_module dsm_gradient_text dsm_gradient_text_0 \">\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t<div class=\"et_pb_module_inner\">\n\t\t\t\t\t<h1 class=\"dsm-gradient-text et_pb_module_header\">NMR Spectroscopy<\/h1>\n\t\t\t\t<\/div>\n\t\t\t<\/div>NMR SpectroscopyNMR SpectroscopyIdentifying StructuresIn NMR spectroscopy, in addition to the classical metabolites from clinical chemistry such as glucose and cholesterol, numerous other measurands like amino acids, medications, and many other substances are detected. The number of identified substances in the libraries [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":252683,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","_view_id":"","footnotes":""},"class_list":["post-252368","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.9 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>NMR Spectroscopy - DGKL<\/title>\n<meta name=\"description\" content=\"NMR Spectroscopy: Detecting metabolites and health risks through NMR spectroscopy. 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